Evans

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• HARVARD HIV AND AGING WORKSHOP: PERSPECTIVES AND PRIORITIES FROM CLAUDE D. PEPPER CENTERS AND CENTERS FOR AIDS RESEARCH.
• SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage.
• Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy.
• Bone marrow-imprinted gut-homing of plasmacytoid dendritic cells (pDCs) in acute simian immunodeficiency virus infection results in massive accumulation of hyperfunctional CD4+ pDCs in the mucosae.
• Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection.
• Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry.
• Characterization of circulating natural killer cells in neotropical primates.
• All-trans-retinoic acid imprints expression of the gut-homing marker 47 while suppressing lymph node homing of dendritic cells.
• Loss of bone marrow NK cells during SIV infection is associated with increased turnover rates and cytotoxicity but not changes in trafficking.
• ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.
• SIV infection induces accumulation of plasmacytoid dendritic cells in the gut mucosa.
• Gut inflammation and indoleamine deoxygenase inhibit IL-17 production and promote cytotoxic potential in NKp44+ mucosal NK cells during SIV infection.
• Flow cytometry based identification of simian immunodeficiency virus Env-specific B lymphocytes.
• KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligand with a Bw6 motif.
• Potential confusion of contaminating CD16+ myeloid DCs with anergic CD16+ NK cells in chimpanzees.
• Quantification of mucosal mononuclear cells in tissues with a fluorescent bead-based polychromatic flow cytometry assay.
• Simian immunodeficiency virus infection induces expansion of alpha4beta7+ and cytotoxic CD56+ NK cells.
• Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1.