The overarching goal of the Reeves & Jost Labs is to delineate mechanisms by which innate immune cells modulate viral infections. Ongoing work includes basic and translational immunologic studies of granulocytes, innate lymphoid cells, and, in particular, memory NK cells. With a global network of partners and cutting edge techniques, our laboratories are harnessing the functional potency of these cells in new immunotherapeutics and vaccines against HIV, influenza, HCV, CMV, and cancer.

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Recent Publications

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The COVID-19 pandemic has caused more than 575,000 deaths worldwide as of mid-July 2020 and still continues globally unabated. Immune …

Natural killer (NK) cells provide some of the earliest immune responses to infection, but when viruses manipulate or perturb the immune …

CD49a+ tissue resident NK cells have been implicated in memory-like NK cell responses, but while this population is well-characterized …



Dimensionality Reduction and Visualization for Flow Cytometry

Attempting to find a transcriptomic signature of single-cell NK clones that respond in a memory-like fasion to HIV antigens.

Our Group

Principal Investigators


Keith Reeves

Associate Professor of Medicine
Director, CFAR ALTC


Stephanie Jost

Assistant Professor of Medicine


Valerie Varner

Research Lab Director

Stephanie Etienne

Program Coordinator

Michelle Lifton

Flow Core Manager

Alexander Cope

Flow Cytometry Tech I

Staff Scientists

Cordelia Manickam

Staff Scientist

Post Doctoral Fellows

Daniel Ram

Post Doctoral Fellow

Sho Sugawara

Post Doctoral Fellow

Philippe Rascle

Post Doctoral Fellow

Research Assistants

Brady Hueber

Research Assistant II

Rhianna Jones

Research Assistant II

Granulocytes, NK Cells, Infectious diseases, Genetic diseases, Flow Cytometry, ImageStream flow cytometry

Kyle Kroll

Aspiring Bioinformatician

Transcriptomics, Memory NK Cells

Griffin Woolley

Research Assistant II

Matthew Mosher

Research Assistant I


Taylor Yoder

Research Assistant I


Lab Alumni

Spandan Shah

Staff Scientist

S. Smith

Research Assistant III


Joshua Ghofrani

Research Assistant II

Innate Immunology, HIV, Influenza, Dietetics


Olivier Lucar

Post Doctoral Fellow

NK cells, HIV, CMV, Flu, Single-Cell Cloning, NKG2C:HLA-E Interactions

Rachel Hindin

Flow Cytometry Tech I

Mercay Reuter

Research Assistant I


Allie Werner



  • National Institute of Allergy and Infectious Diseases
  • National Institute of Dental and Craniofacial Research
  • NIAID Consortia for Innovative AIDS Research in Nonhuman Primates
  • Harvard University Center for AIDS Research (CFAR)
  • The Foundation for AIDS Research (amfAR)
  • HIV Vaccine Trials Network (HVTN)

Collabortions & Affilates

Technologies Utilized

Flow Cytometry

NHP and Human Models





Flow Cytometry Core

  • BD FACSSymphony A5
  • BD FACSAria II
    • COMS approved facility allows for sterile sorting of fixed and unfixed human, non-human primate, and other animal specimens for HCV and HIV/AIDS research. BD FACS Aria II cell sorter equipped within a Bioprotect IV LE biosafety cabinet operates with 4 solid state lasers: 405nm violet measuring up to 8 parameters, 488nm blue measuring up to 2 parameters in addition to FSC and SSC, 532nm green measuring up to 5 parameters, and a 628nm red measuring up to 3 parameters, allowing sorting panels of up to 18 fluorescent markers.
    • Two BD LSR II analyzers, each equipped with 4 solid state lasers: 405nm violet measuring up to 7 parameters, 488nm blue measuring up to 5 parameters in addition to FSC and SSC, a 640nm red measuring up to 3 parameters, and a 355 nm UV laser measuring 3 parameters allowing panels of up to 18 fluorescent markers
  • BD LSRFortressa X14
    • Special research product with a choice of 3 solid state lasers a 405nm violet measuring up to 6 parameters, 488nm blue measuring up to 2 parameters in addition to FSC and SSC, a 561nm Yellow/Green measuring up to 4 parameters allowing panels of up to 12 fluorescent markers
  • Siemens ADVIA 120 Hematology System
    • Multispecies analyzing system for complete blood count and differential counts