Sirignano

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• Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation.
• Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM.
• Increased frequency and function of KIR2DL1-3 NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.