Rihn

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• Reduced frequencies of NKp30+NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance.
• MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction.
• Matrix metalloprotease inhibitors restore impaired NK cell-mediated antibody-dependent cellular cytotoxicity in human immunodeficiency virus type 1 infection.