Estes

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• Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells.
• Intestinal damage precedes mucosal immune dysfunction in SIV infection.
• Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function.
• SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage.
• Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy.
• Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection.