Carrington

Latest

• HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells.
• Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.
• KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligand with a Bw6 motif.
• MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction.