Altfeld

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• HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells.
• Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.
• Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01.
• Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation.
• Antigen-specific NK cell memory in rhesus macaques.
• Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM.
• Increased frequency and function of KIR2DL1-3 NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.
• CD4+ T-cell help enhances NK cell function following therapeutic HIV-1 vaccination.
• Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection.
• Control of human viral infections by natural killer cells.
• Harnessing innate and adaptive immunity for viral vaccine design.
• Evasion from NK cell-mediated immune responses by HIV-1.
• Changes in cytokine levels and NK cell activation associated with influenza.
• KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligand with a Bw6 motif.
• Expansion of 2B4+ natural killer (NK) cells and decrease in NKp46+ NK cells in response to influenza.
• Reduced frequencies of NKp30+NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance.
• MHC class I chain-related protein A shedding in chronic HIV-1 infection is associated with profound NK cell dysfunction.