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Persistent Low-Level Replication of SIVnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection.
Characterization of CD8+ T cell differentiation following SIVnef vaccination by transcription factor expression profiling.
CD8 T cell response maturation defined by anentropic specificity and repertoire depth correlates with SIVnef-induced protection.
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